Non-linear impact of glutathione depletion on C. elegans life span and stress resistance
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چکیده
منابع مشابه
Non-linear impact of glutathione depletion on C. elegans life span and stress resistance
The redox environment in cells and organisms is set by low-molecular mass and protein-bound thiols, with glutathione (GSH) representing a major intracellular redox buffer. Subtle thiol oxidation elicits signal transduction processes and adaptive responses to cope with stressors, whereas highly oxidizing conditions may provoke cell death. We here tested how thiol depletion affects life span, str...
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ژورنال
عنوان ژورنال: Redox Biology
سال: 2017
ISSN: 2213-2317
DOI: 10.1016/j.redox.2016.12.003